WebNov 3, 2024 · Antibiotics, Antivirals, and Antiparasitic Drugs. Erythromycin (antibiotic) Interaction may not be clinically important . ... When simvastatin is taken 24 hours after taking a “high dose” of grapefruit juice, the effect is only about 10% of the effect observed when grapefruit juice and simvastatin are taken at the same time [85, 86]. WebJan 15, 2024 · All citrus juices profoundly induced several drug transporters and drug metabolising enzymes, whereas the effects of grapefruit juice were most pronounced (e.g. 156-fold and 34-fold induction of cytochrome P450 (CYP) 3A4 mRNA by grapefruit juice and clementine juice, respectively). ... Antibiotics, Antitubercular / adverse effects …
Why Grapefruit Affects Your Medication - SelfDecode Drugs
WebJul 31, 2024 · For more information, please visit our page on clindamycin and alcohol interactions. Clindamycin and Grapefruit Juice. According to the FDA, grapefruit and grapefruit juice can negatively interact with many drugs, including antibiotics.This interference is due to compounds in grapefruit juice that can increase the amount of a … WebDec 26, 2024 · Grapefruit juice inhibits this enzyme. When the enzyme can’t process the medication as efficiently, the drug levels can build up, causing worsened or more severe side effects . If too much atorvastatin or another statin builds up in your body, you can suffer from liver and muscle damage and even kidney failure. raw meat side effects
These 11 Medications Interact With Grapefruit Juice - GoodRx
WebGrapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body ... WebJul 1, 2007 · Eating grapefruit or drinking grapefruit juice affects how your body processes certain medicines. The chemicals in grapefruit can cause your body to absorb either too much or too little medicine into your bloodstream. This makes it more likely that you will experience side effects from the medicine, or that your medicine won’t be effective. WebFeb 2, 2024 · Medically reviewed by Chris Vincent, MD. Fact checked by Marley Hall. Print. While grapefruit juice is rich in nutrients, it may cause interactions with some … simplehuman mirror warranty